The number of aged and disabled people has been increasing worldwide. To look after these people is a big challenge in this era. However, scientists overcome the problems of handicapped people with the help of the latest communication technologies. The smart home and medical systems are a predominant concept in research and development, specially utilizing the brain-computer interface (BCI) technology to control the daily use appliances. BCI acquires the brain signals that transmit to a digital device for analyzing and interpreting into further command or action but this approach limits the communication range between the brain and the system and becomes bulky because of the wired interface of a brain with the system. Therefore, the main purpose of this research was to design and evaluate a system that empowered the immobilized, handicapped or elderly people to carry out their basic routine tasks wirelessly, for instance, operating home appliances and monitoring vital signs without any dependency. In addition, the subject should have a properly functioning brain and controlled with eye muscle movement. In this research work, wireless BCI (WBCI) technology that is a commercial electroencephalogram headset is used to control home and medical appliances such as a light bulb, a fan, a digital blood pressure monitor and an Infrared deep pain therapeutic belt for dependent people. An Android application is developed name “Smart Home Monitor” that monitors the data from the headset. The designed device is tested on younger (50-year-old) and older (> 50-year-old) individuals to achieve an attention level (0–100). The younger male reached attention level 74.78 within 26.20 s; quicker than younger female and older people. Overall, this research work is unique for the reason that it is suitable for all those people, whose brain and eye muscles are functional even if the rest of the body is paralyzed. This analysis evaluated WBCI device enables the system to be wireless, handy, portable and reliable. Thus, the whole system can be commercialized for immobilized or handicapped people to provide better care and facility at home. Especially, the disable people appreciated this system and want to see its implementation as soon as possible.